Dr. Peter Blume, co-director of chronic limb ischemia at Yale New Haven hospital is involved in a clinical trial entitled: BEST CLI trial
Peripheral Arterial Disease is a condition where plaque builds up in the blood vessels that carry blood to the arms and legs. In some of these patients, the blockage creates a narrowing so severe that blood cannot get to the foot. This is called Critical Limb Ischemia, and sometimes feels like foot pain at rest or foot and leg ulcerations. CLI is a very serious disease that can lead to gangrene and the loss of the foot or leg.
Together with Yale, we are participating in a ground breaking trial, entitled BEST CLI, to try and help these patients. BEST CLI is a randomized comparison trial designed to evaluate the effectiveness of best surgical practice with best endovascular treatment in patients with Critical Limb Ischemia. The study is going to be enrolling 2100 patients across the country, and aims to help patients save their legs and feet. Patients will be randomized to either having a bypass surgery, or an angioplasty/stent within their leg. Patients enrolled in the trial will be very closely followed by a multidisciplinary team, including Interventional Cardiologists, Vascular Surgeons, and Podiatry.